[Dpr3]ghrelin(1-20)

[Dpr3]ghrelin(1-20) is an experimental **ghrelin peptide analogue** derived from the N-terminal 20-amino-acid fragment of ghrelin, with substitution of **diaminopropionic acid at residue 3** to preserve the acylation handle required for receptor recognition while enabling chemical optimization. It has been studied in preclinical medicinal chemistry programs as a **growth hormone secretagogue receptor agonist scaffold** for improving ghrelin-like activity, receptor affinity, helicity, and proteolytic stability, including as a precursor framework for stapled ghrelin analogues. The available evidence indicates this is a research-stage peptide tool compound rather than a clinically developed therapeutic product, with no identified brand, company-sponsored development program, or marketed formulation.

Other names

Dpr3-ghrelin(1-20)ghrelin(1-20) analogue with Dpr at position 3